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https://has.hcu.ac.th/jspui/handle/123456789/1829
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DC Field | Value | Language |
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dc.contributor.author | Adchara Prommaban | - |
dc.contributor.author | Suwannee Sriyab | - |
dc.contributor.author | Pachabadee Marsup | - |
dc.contributor.author | Waranya Neimkhum | - |
dc.contributor.author | Jakkapan Sirithunyalug | - |
dc.contributor.author | Songyot Anuchapreeda | - |
dc.contributor.author | Chaiwat To-anun | - |
dc.contributor.author | Wantida Chaiyana | - |
dc.contributor.author | อัจฉรา พรมมาแบน | - |
dc.contributor.author | สุวรรณี ศรียาบ | - |
dc.contributor.author | วรัญญา เนียมขำ | - |
dc.contributor.author | จักรพันธ์ ศิริธัญญาลักษณ์ | - |
dc.contributor.author | ทรงยศ อนุชปรีดา | - |
dc.contributor.author | ชัยวัฒน์ โตอนันต์ | - |
dc.contributor.author | วรรธิดา ชัยญาณะ | - |
dc.contributor.author | ปชาบดี มาทรัพย์ | - |
dc.contributor.other | Chiang Mai University. Faculty of Pharmacy | th |
dc.contributor.other | Chiang Mai University. Faculty of Pharmacy | th |
dc.contributor.other | Chiang Mai University. Faculty of Pharmacy | th |
dc.contributor.other | Huachiew ChalermprakietUniversity. Faculty of Pharmaceutical Sciences | th |
dc.contributor.other | Chiang Mai University. Research Center of Pharmaceutical Nanotechnology | th |
dc.contributor.other | Chiang Mai University. Faculty of Associated Medical Sciences | th |
dc.contributor.other | Chiang Mai University. Faculty of Agriculture | th |
dc.contributor.other | Chiang Mai University. Faculty of Pharmacy | th |
dc.date.accessioned | 2024-03-07T13:41:15Z | - |
dc.date.available | 2024-03-07T13:41:15Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Pharmaceutical Biology 60,1 (2022) : 225-234. | th |
dc.identifier.other | https://doi.org/10.1080/13880209.2021.2025255 | - |
dc.identifier.uri | https://has.hcu.ac.th/jspui/handle/123456789/1829 | - |
dc.description | สามารถเข้าถึงบทความฉบับเต็มได้ที่ https://www.tandfonline.com/doi/epdf/10.1080/13880209.2021.2025255?needAccess=true | th |
dc.description.abstract | Context Cordyceps militaris and Isaria tenuipes (Cordycipitaceae) are high-value fungi that are used for health-promoting food supplements. Since laboratory cultivation has begun for these fungi, increased output has been achieved. Objective This study compared the chemical profiles, antioxidant, anti-tyrosinase, and skin extracellular matrix degradation inhibition between mycelium and fruiting body of C. militaris and I. tenuipes. Materials and methods The antioxidative potential of 10% v/v aqueous infused extract from each fungus was separately investigated using 2,2-azinobis(3-ethylbenzo-thiazoline-6-sulphonic acid) (ABTS), 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing antioxidant ability, and ferric thiocyanate methods. The inhibition against MMP-1, elastase, and hyaluronidase were determined to reveal their anti-wrinkle potential. Anti-tyrosinase activities were determined. Results C. militaris and I. tenuipes extracts were found to contain a wide range of bioactive compounds, including phenolics, flavonoids, and adenosine. A correlation was discovered between the chemical compositions and their biological activities. The extract from I. tenuipes fruiting body (IF) was highlighted as an extraordinary elastase inhibitor (IC50 = 0.006 ± 0.004 mg/mL), hyaluronidase inhibitor (IC50: 30.3 ± 3.2 mg/mL), and antioxidant via radical scavenging (ABTS IC50: 0.22 ± 0.02 mg/mL; DPPH IC50: 0.05 ± 0.02 mg/mL), thereby reducing ability (EC1: 95.3 ± 4.8 mM FeSO4/g extract) and lipid peroxidation prevention (IC50: 0.40 ± 0.11 mg/mL). IF had a three-times higher EC1 value than ascorbic acid and significantly higher elastase inhibition than epigallocatechin gallate. Discussion and conclusions IF is proposed as a powerful natural extract with antioxidant and anti-wrinkle properties; therefore, it is suggested for further use in pharmaceutical, cosmeceutical, and nutraceutical industries. | th |
dc.language.iso | th | th |
dc.subject | คอร์ไดซิปิน | th |
dc.subject | Cordycepin | th |
dc.subject | อะดีโนซีน | th |
dc.subject | Adenosine | th |
dc.subject | อายุวัฒนะ | th |
dc.subject | Anti-aging | th |
dc.subject | ผิวหนัง -- รอยย่น | th |
dc.subject | Skin -- Wrinkles | th |
dc.subject | Anti-wrinkle | th |
dc.title | Comparison of chemical profiles, antioxidation, inhibition of skin extracellular matrix degradation, and anti-tyrosinase activity between mycelium and fruiting body of Cordyceps militaris and Isaria tenuipes | th |
dc.type | Article | th |
Appears in Collections: | Pharmaceutical Sciences - Artical Journals |
Files in This Item:
File | Description | Size | Format | |
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Cordycepin.pdf | 60.17 kB | Adobe PDF | View/Open |
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