Please use this identifier to cite or link to this item: https://has.hcu.ac.th/jspui/handle/123456789/2722
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dc.contributor.authorThawanratn Pinya-
dc.contributor.authorAekkhaluck Intharuksa-
dc.contributor.authorSuthira Yanaso-
dc.contributor.authorSuthiwat Kamnuan-
dc.contributor.authorAmpai Phrutivorapongkul-
dc.contributor.authorเอกลักษณ์ อินทรักษา-
dc.contributor.authorสุธีรา ญานะโส-
dc.contributor.authorอำไพ พฤติวรพงศ์กุล-
dc.contributor.otherChiang Mai University. Faculty of Pharmacyen
dc.contributor.otherChiang Mai University. Faculty of Pharmacyen
dc.contributor.otherHuachiew Chalermprakiet University. Faculty of Pharmaceutical Sciencesen
dc.contributor.otherChiang Mai University. Faculty of Pharmacyen
dc.contributor.otherChiang Mai University. Faculty of Pharmacyen
dc.date.accessioned2024-08-28T08:40:15Z-
dc.date.available2024-08-28T08:40:15Z-
dc.date.issued2022-
dc.identifier.citationJournal of Natural Medicines (2022) 76:605–620en
dc.identifier.otherhttps://doi.org/10.1007/s11418-022-01607-4-
dc.identifier.urihttps://has.hcu.ac.th/jspui/handle/123456789/2722-
dc.descriptionสามารถเข้าถึงบทความฉบับเต็มได้ที่ (Full text) : https://link.springer.com/article/10.1007/s11418-022-01607-4en
dc.description.abstractThe morphological and microscopy were combined with DNA-barcoding, together with rapid TLC for the characterization of Piper betle (PB), P. nigrum (PN), P. retrofractum (PR), P. sarmentosum (PS), and P. wallichii (PW), five medicinal Piper plants announced in the Thai Herbal Pharmacopoeia (THP). The authentic plants collected from various locations and voucher Piper products bought from commercial sites in Thailand were studied. The reproductive parts of authentic plants were subjected to ensure their morphological characters. Using sequencing analysis and genetic divergence for analyzing discriminatory performance, ITS2 was selected from eight candidate DNA markers to authenticate the origin of Piper crude drugs together with microscopic and TLC profles for examining their characters, admixtures, adulterants, and substituents. PB and PR exhibited unique characters of the species, with no admixture, adulteration, and substitution. PN showed no variable characters of morphology and genetics. However, the microscopy could illustrate some commercial products of PN sold in Thailand have been adulterated with rice starch and roasted rice. In the herbal trade, PS has been sold in the form of mixed leaf, root, and stem more than the isolated part, but there is no variable character of the species. PW has shown more than one character of species explained by microscopic, chemical components, and genetic data. In conclusion, the conventional and molecular pharmacognostic data combined with chemical profile of authentic five Piper plants could be applied to indicate the plant origin and clarify the situations of admixture, adulteration, and substitution of the commercial Piper products launched in Thailand.en
dc.language.isoen_USen
dc.subjectPiperaceae familyen
dc.subjectพืชวงศ์พริกไทยen
dc.subjectThai Herbal Pharmacopoeiaen
dc.subjectตำรามาตรฐานยาสมุนไพรไทยen
dc.subjectPlants, Medicinal -- Thailanden
dc.subjectพืชสมุนไพร -- ไทยen
dc.subjectDNA Barcodingen
dc.subjectดีเอ็นเอบาร์โคดen
dc.titleConventional and molecular pharmacognostic characters integrated with chemical profiles of five Piper plants in the Thai herbal pharmacopoeia and their dmixture/adulteration/substitution situations in Thailanden
dc.typeArticleen
Appears in Collections:Pharmaceutical Sciences - Artical Journals

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