1. Huachiew Chalermprakiet University
  2. มหาวิทยาลัยหัวเฉียวเฉลิมพระเกียรติ
  3. คณะเภสัชศาสตร์
  4. Pharmaceutical Sciences - Artical Journals
Please use this identifier to cite or link to this item: https://has.hcu.ac.th/jspui/handle/123456789/3669
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dc.contributor.authorSongyot Anuchapreeda-
dc.contributor.authorRiki Anzawa-
dc.contributor.authorNatsima Viriyaadhammaa-
dc.contributor.authorWaranya Neimkhum-
dc.contributor.authorWantida Chaiyana-
dc.contributor.authorSiriporn Okonogi-
dc.contributor.authorToyonobu Usuki-
dc.contributor.authorทรงยศ อนุชปรีดา-
dc.contributor.authorวรัญญา เนียมขำ-
dc.contributor.authorวรรธิดา ชัยญาณะ-
dc.contributor.authorศิริพร โอโกโนกิ-
dc.contributor.otherChiang Mai University. Faculty of Associated Medical Sciencesen
dc.contributor.otherSophia University. Faculty of Science and Technology (Tokyo)en
dc.contributor.otherChiang Mai University. Faculty of Associated Medical Sciencesen
dc.contributor.otherHuachiew Chalermprakiet University. Faculty of Pharmaceutical Sciencesen
dc.contributor.otherChiang Mai University. Faculty of Pharmacyen
dc.contributor.otherChiang Mai University. Faculty of Pharmacyen
dc.contributor.otherSophia University. Faculty of Science and Technology (Tokyo)en
dc.date.accessioned2025-02-14T14:30:25Z-
dc.date.available2025-02-14T14:30:25Z-
dc.date.issued2020-
dc.identifier.citationBioorg Med Chem Lett 2020 Jul 15;30(14):127256en
dc.identifier.otherdoi: 10.1016/j.bmcl.2020.127256-
dc.identifier.urihttps://has.hcu.ac.th/jspui/handle/123456789/3669-
dc.descriptionสามารถเข้าถึงบทความฉบับเต็ม (Full Text) ได้ที่ : https://pubmed.ncbi.nlm.nih.gov/32527555/en
dc.description.abstractThe leaves of the kaffir lime (Citrus hystrix) are commonly used in cuisine and folk medicine. The aim of this study was to isolate a bioactive compound in kaffir lime leaves and characterize its biological activity. The compound was isolated from a hexane fractional extract and identified as agrostophillinol. This is the first report of agrostophillinol isolated from kaffir lime leaves. In terms of cytotoxicity, agrostophillinol exhibited IC50 values of 36.27 ± 7.30 and 53.44 ± 10.63 μg/mL against EoL-1 and HL60 cells, respectively. Agrostophillinol also exhibited potent anti-inflammatory activity, significantly inhibiting IL-6 secretion.en
dc.language.isoen_USen
dc.subjectAnticanceren
dc.subjectยารักษามะเร็งen
dc.subjectAntioxidantsen
dc.subjectแอนติออกซิแดนท์en
dc.subjectAnti-inflammatory agentsen
dc.subjectสารต้านการอักเสบen
dc.subjectAntibioticsen
dc.subjectแอนติบอดีย์en
dc.subjectBioactive compoundsen
dc.subjectสารออกฤทธิ์ทางชีวภาพen
dc.subjectCitrus hystrix -- Leavesen
dc.subjectมะกรูด – ใบen
dc.subjectKaffir limeen
dc.subjectAgrostophillinolen
dc.titleIsolation and biological activity of agrostophillinol from kaffir lime (Citrus hystrix) leavesen
dc.typeArticleen
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