Isaya Janwitayanuchit; Suwanna Semsri; Wicharn Janwitayanuchit; Kiattawee Choowongkomon(Journal of Associated Medical Sciences, 2024)
Background: Mangiferin, a natural compound has been reported to possess a variety of biological activities such as anticancer, anti-diabetic, antimicrobial, antioxidant, cardioprotective activities, etc. Screening on blood ...
HLA-B*13:01 allele has been identified as the genetic determinant of dapsone hypersensitivity syndrome (DHS) among leprosy and non-leprosy patients in several studies. Dapsone hydroxylamine (DDS-NHOH), an active metabolite ...
Qing Zhao; Mubarak Almutairi; Arun Tailor; Adam Lister; Nicolas Harper; James Line; Xiaoli Meng; Jirawat Pratoomwun; Kanoot Jaruthamsophon; Chonlaphat Sukasem; Yonghu Sun; Lele Sun; Monday O Ogese; David J MacEwan; Munir Pirmohamed; Jianjun Liu; David A Ostrov; Hong Liu; Furen Zhang; Dean J Naisbitt; จิรวัส ประทุมวัน; คณุตม์ จารุธรรมโสภณ; ชลภัทร สุขเกษม(2021)
HLA-B∗13:01 is associated with dapsone (DDS)-induced hypersensitivity, and it has been shown that CD4+ and CD8+ T cells are activated by DDS and its nitroso metabolite (nitroso dapsone [DDS-NO]). However, there is a need ...
HLA-B*13:01-positive patients in Thailand can develop frequent co-trimoxazole hypersensitivity reactions. This study aimed to characterize drug-specific T cells from three co-trimoxazole hypersensitive patients presenting ...
Prior knowledge of allele frequencies of cytochrome P450 polymorphisms in a population is crucial for the revision and optimization of existing medication choices and doses. In the current study, the frequency of the ...
The aim of this study was to investigate the antimalarial activities and toxicity of Pogostemon cablin extracts. In vitro activities against the chloroquine-resistant Plasmodium falciparum K1 strain were assessed by using ...
Background: High glucose (HG)-induced reactive oxygen species (ROS) overproduction impairs angiogenesis that is one pivotal factor of wound healing process. Angiogenesis impairment induces delayed wound healing, whereby ...
The increasing popularity of Chinese herbal treatment has sparked interest in investigating how safe these alternative medicines are. This study scrutinized the Chinese herbs used most popularly in Thailand to identify the ...
Recently, many antibacterial agents have been found in the venoms of animals from different sources. However, multidrug-resistant strains of bacteria are an important health problem in need for new antibacterial sources ...
Diabetes mellitus constitutes one of the most important public health problems. It is defined as a metabolic disorder characterized by a chronic hyperglycemic condition. The inhibition of α-glucosidase and inflammation ...